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Lanostane Triterpenes Isolated from Antrodia heteromorpha and Their Inhibitory Effects on RANKL-Induced Osteoclastogenesis

Authors
Kwon, JaeyoungLee, HyaeminYoon, Yeo DaeHwang, Bang YeonGuo, YuanqiangKang, Jong SoonKim, Jae-JinLee, Dongho
Issue Date
6월-2016
Publisher
AMER CHEMICAL SOC
Citation
JOURNAL OF NATURAL PRODUCTS, v.79, no.6, pp.1689 - 1693
Indexed
SCIE
SCOPUS
Journal Title
JOURNAL OF NATURAL PRODUCTS
Volume
79
Number
6
Start Page
1689
End Page
1693
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/88464
DOI
10.1021/acs.jnatprod.6b00207
ISSN
0163-3864
Abstract
Two new spiro-lanostane triterpenoids, antrolactones A and B (1 and 2), along with polyporenic acid C (3), were isolated from an EtOAc-soluble extract of Antrodia heteromorpha culture medium, and the chemical structures of the new compounds were elucidated by application of NMR, MS, and ECD spectroscopic techniques. All isolated compounds exhibited inhibitory effects on receptor activator of nuclear factor-kappaB ligand-induced osteoclastogenesis.
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College of Life Sciences and Biotechnology > Division of Environmental Science and Ecological Engineering > 1. Journal Articles
Graduate School > Department of Plant Biotechnology > 1. Journal Articles

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생명과학대학 (환경생태공학부)
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