Poly(ether imide)-silica hybrid coatings for tunable corrosion behavior and improved biocompatibility of magnesium implants
- Authors
- Kang, Min-Ho; Jang, Tae-Sik; Jung, Hyun-Do; Kim, Sae-Mi; Kim, Hyoun-Ee; Koh, Young-Hag; Song, Juha
- Issue Date
- 6월-2016
- Publisher
- IOP PUBLISHING LTD
- Keywords
- hybrid coating; silica; biodegradation; corrosion resistance; magnesium; hard tissue engineering
- Citation
- BIOMEDICAL MATERIALS, v.11, no.3
- Indexed
- SCIE
SCOPUS
- Journal Title
- BIOMEDICAL MATERIALS
- Volume
- 11
- Number
- 3
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/88561
- DOI
- 10.1088/1748-6041/11/3/035003
- ISSN
- 1748-6041
- Abstract
- Magnesium (Mg) and its alloys have gained considerable attention as a promising biomaterial for bioresorbable orthopedic implants, but the corrosion behavior of Mg-based implants is still the major issue for clinical use. In order to improve the corrosion stability and implant-tissue interfaces of these implants, methods for coating Mg have been actively investigated. In this study, poly(ether imide) (PEI)silica hybrid material was coated on Mg, for the tunable degradation and enhanced biological behavior. Homogeneous PEI-silica hybrid materials with various silica contents were coated on Mg substrates without any cracks, where silica nanoparticles were well dispersed in the PEI matrix without significant particle agglomeration up the 30 vol% silica. The hybrid coatings maintained good adhesion strength of PEI to Mg. The corrosion rate of hybrid-coated Mg was increased along with the increment of the silica content, due to improved hydrophilicity of the hybrid coating layers. Moreover, the biocompatibility of the hybrid-coated Mg specimens was significantly improved, mainly due to the higher Mg ion concentrations associated with faster corrosion, compared to PEI-coated Mg. Therefore, PEI-silica hybrid systems have significant potential as a coating material of Mg for load-bearing orthopedic applications by providing tunable corrosion behavior and enhanced biological performance.
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Collections - Graduate School > Department of Bioengineering > 1. Journal Articles
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