Association between Snoring and Leukocyte Telomere Length
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Chol | - |
dc.contributor.author | Yun, Chang-Ho | - |
dc.contributor.author | Yoon, Dae Wui | - |
dc.contributor.author | Baik, Inkyung | - |
dc.date.accessioned | 2021-09-04T00:48:33Z | - |
dc.date.available | 2021-09-04T00:48:33Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2016-04-01 | - |
dc.identifier.issn | 0161-8105 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/88946 | - |
dc.description.abstract | Study Objectives: Data on the association between snoring and telomere length, an indicator of biological aging, are very limited. Moreover, no polysomnography (PSG) studies on this association in a general population have been conducted. Our study aimed to evaluate the association between snoring and leukocyte telomere length (LTL) using PSG and a questionnaire. Methods: A cross-sectional PSG study embedded in a population-based cohort from the Korean Genome Epidemiology Study was conducted in 2010-2013. During the same period, questionnaire-based interviews, blood collection, and relative LTL assays were conducted. A total of 887 Korean men and women aged 50-79 y with an apnea-hypopnea index (AHI) < 15 determined in the PSG study were included in the study. Results: We observed that the percentage of time spent snoring during sleep (% time spent snoring) assessed by PSG was inversely associated with LTL even after adjusting for potential risk factors and AHI. In the linear regression association between tertiles of percentage of time spent snoring and log-transformed LTL, coefficient estimates (P value) were -0.076 (< 0.05) for the second tertile and -0.084 (< 0.01) for the third tertile compared with the bottom tertile. When LTL was compared according to snoring status determined using PSG and questionnaire information, both primary snorers and those with mild sleep apnea (5 <= AHI < 15) had shorter LTL than nonsnorers. Conclusions: Our findings suggest that snoring may influence telomere attrition independent of sleep apnea. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS INC | - |
dc.subject | OBSTRUCTIVE SLEEP-APNEA | - |
dc.subject | AIRWAY INFLAMMATION | - |
dc.subject | OXIDATIVE STRESS | - |
dc.subject | VIBRATION | - |
dc.subject | CHILDREN | - |
dc.subject | MODEL | - |
dc.title | Association between Snoring and Leukocyte Telomere Length | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Chol | - |
dc.identifier.doi | 10.5665/sleep.5624 | - |
dc.identifier.scopusid | 2-s2.0-84962425222 | - |
dc.identifier.wosid | 000373186900008 | - |
dc.identifier.bibliographicCitation | SLEEP, v.39, no.4, pp.767 - 772 | - |
dc.relation.isPartOf | SLEEP | - |
dc.citation.title | SLEEP | - |
dc.citation.volume | 39 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 767 | - |
dc.citation.endPage | 772 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | OBSTRUCTIVE SLEEP-APNEA | - |
dc.subject.keywordPlus | AIRWAY INFLAMMATION | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.subject.keywordPlus | VIBRATION | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordAuthor | population-based study | - |
dc.subject.keywordAuthor | leukocyte telomere length | - |
dc.subject.keywordAuthor | polysomnography | - |
dc.subject.keywordAuthor | snoring | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.