Evaluation of the Performance of a Fecal Tumor M2-PK Rapid Kit Using Stool Specimens for Detection of Colorectal Tumors
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Chi Hyun | - |
dc.contributor.author | Kim, Jeeyong | - |
dc.contributor.author | Jang, Mi Ae | - |
dc.contributor.author | Lee, Beom Jae | - |
dc.contributor.author | Park, Jong-Jae | - |
dc.contributor.author | Lim, Chae Seung | - |
dc.date.accessioned | 2021-09-04T02:09:30Z | - |
dc.date.available | 2021-09-04T02:09:30Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2016-03 | - |
dc.identifier.issn | 0091-7370 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/89353 | - |
dc.description.abstract | Background. In gastrointestinal tumors, only subunits of pyruvate kinase isoenzyme type M2 are detectable, and mainly in the dimeric form termed tumor M2-PK. A rapid test for the detection of M2PK in stool has been developed. We evaluated the performance of the M2-PK rapid kit for the detection of colorectal tumors compared with colonoscopy. Design. Stool specimens (n= 268) were obtained from patients who had a fecal occult blood test and colonoscopy performed for clinical evaluation or routine health checkup. Collected stool specimens were kept frozen at -20 degrees C until testing. The fecal tumor M2-PK test was performed using a ScheBo M2-PK Quick test (ScheBo((R)) center dot Biotech AG, Giessen, Germany). Results. A total of 236 patients were analyzed, including 87 with tubular adenoma and 126 controls. In tumor M2PK testing, 37 of 87 tubular adenoma specimens (42.5%) and 2 of 4 sessile serrated adenoma specimens (50%) tested positive. The specificity of the M2-PK rapid test was 87.3%. Conclusion. The tumor M2-PK test demonstrated moderate sensitivity for detection of colorectal adenoma. M2-PK test could be considered as a useful point-of-care testing device for detection of colorectal tumors. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ASSOC CLINICAL SCIENTISTS | - |
dc.subject | M2 PYRUVATE-KINASE | - |
dc.subject | M2-PYRUVATE KINASE | - |
dc.subject | GASTRIC-CANCER | - |
dc.subject | TESTS | - |
dc.subject | MARKER | - |
dc.subject | INFLAMMATION | - |
dc.subject | ADENOMAS | - |
dc.subject | DISEASE | - |
dc.subject | POLYPS | - |
dc.title | Evaluation of the Performance of a Fecal Tumor M2-PK Rapid Kit Using Stool Specimens for Detection of Colorectal Tumors | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Cho, Chi Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Jeeyong | - |
dc.contributor.affiliatedAuthor | Lee, Beom Jae | - |
dc.contributor.affiliatedAuthor | Park, Jong-Jae | - |
dc.contributor.affiliatedAuthor | Lim, Chae Seung | - |
dc.identifier.scopusid | 2-s2.0-84966539209 | - |
dc.identifier.wosid | 000388921300005 | - |
dc.identifier.bibliographicCitation | ANNALS OF CLINICAL AND LABORATORY SCIENCE, v.46, no.2, pp.154 - 160 | - |
dc.relation.isPartOf | ANNALS OF CLINICAL AND LABORATORY SCIENCE | - |
dc.citation.title | ANNALS OF CLINICAL AND LABORATORY SCIENCE | - |
dc.citation.volume | 46 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 154 | - |
dc.citation.endPage | 160 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Medical Laboratory Technology | - |
dc.relation.journalWebOfScienceCategory | Medical Laboratory Technology | - |
dc.subject.keywordPlus | M2 PYRUVATE-KINASE | - |
dc.subject.keywordPlus | M2-PYRUVATE KINASE | - |
dc.subject.keywordPlus | GASTRIC-CANCER | - |
dc.subject.keywordPlus | TESTS | - |
dc.subject.keywordPlus | MARKER | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | ADENOMAS | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | POLYPS | - |
dc.subject.keywordAuthor | M2-PK | - |
dc.subject.keywordAuthor | colorectal tumor | - |
dc.subject.keywordAuthor | stool | - |
dc.subject.keywordAuthor | rapid test | - |
dc.subject.keywordAuthor | colonoscopy | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.