Detailed Information
Cited 0 time in 
Cited 0 time in 
Cited 0 time in
Metadata Downloads
Evaluation of safety and efficacy of adipose-derived stem cells in rat myocardial infarction model using hexadecyl-4-[I-124]iodobenzoate for cell tracking
- Authors
- Kim, Min Hwan; Lee, Kyo Chul; An, Gwang Il; Woo, Sang-Keun; Park, Noh Won; Kim, Byung Il; Eom, Ki Dong; Kim, Kwang Il; Lee, Tae Sup; Kim, Chan Wha; Yoo, Jeongsoo; Kang, Joo Hyun; Lee, Yong Jin
- Issue Date
- 2월-2016
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Keywords
- Adipose-derived stem cells; Hexadecyl-4-[I-124]iodobenzoate; Direct labeling agent; Microarray; Myocardial infarction
- Citation
- APPLIED RADIATION AND ISOTOPES, v.108, pp.116 - 123
- Indexed
- SCIE
SCOPUS
- Journal Title
- APPLIED RADIATION AND ISOTOPES
- Volume
- 108
- Start Page
- 116
- End Page
- 123
- ISSN
- 0969-8043
- Abstract
- This study was aimed to evaluate the effect of I-124-labeling with hexadecyl-4-iodobenzoate (HIB) on gene expression related to cell cycle, DNA repair, transcription, proliferation and differentiation of adipose derived stem cells (ADSCs). [I-124]HIB showed high labeling efficiency with ADSCs (51.3 +/- 1.3%, 0.3-2.0 Bq/cell) and there is no morphological change of ADSCs. In the microarray analysis of gene expression pattern, differences were not observed between non-labeled and [I-124]HIB-labeled ADSCs. We demon-strated that I-124-labeling with HIB did not affect the biological properties of ADSCs. (C) 2015 Elsevier Ltd. All rights reserved.
- Files in This Item
- There are no files associated with this item.
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.