Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Metabolic syndrome in the non-pregnant state is associated with the development of preeclampsia

Authors
Cho, Geum JoonPark, Jong HeonShin, Soon-AeOh, Min-JeongSeo, Hong Seog
Issue Date
15-1월-2016
Publisher
ELSEVIER IRELAND LTD
Keywords
Pre-pregnancy; Metabolic syndrome; Preeclampsia; Hypertension
Citation
INTERNATIONAL JOURNAL OF CARDIOLOGY, v.203, pp.982 - 986
Indexed
SCIE
SCOPUS
Journal Title
INTERNATIONAL JOURNAL OF CARDIOLOGY
Volume
203
Start Page
982
End Page
986
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/89793
DOI
10.1016/j.ijcard.2015.11.109
ISSN
0167-5273
Abstract
Background: The aim of this study was to investigate the association between metabolic syndrome in the nonpregnant state and the development of preeclampsia. Methods: We enrolled 212,463 Korean women who had their first delivery between January, 2011 and December, 2012 and had undergone a national health screening examination through the National Health Insurance during the 1-2 years before their first delivery. Women who had hypertension in the non-pregnant state were excluded. The presence of metabolic syndrome was defined using the modified criteria published in National Cholesterol Education Program Adult Treatment Panel III criteria. Results: The prevalence of metabolic syndrome in non-pregnant state was 1.2%. Preeclampsia developed in 3.1% and its prevalence among women with and without metabolic syndrome was 7.3% and 3.0%, respectively. The pre-pregnancy prevalence of metabolic syndrome was higher in women who developed preeclampsia compared to that in those who had a normal pregnancy (1.1% vs. 2.8%; p < 0.001). On multivariate regression analysis, women with metabolic syndrome had an increased risk of developing preeclampsia (odds ratio: 1.48; 95% CI: 1.26 to 1.74) compared to that in those without metabolic syndrome, after adjusting for age, family history of hypertension, smoking status, and pre-pregnancy body mass index. The risk of preeclampsia increased with a rise in the number of components of metabolic syndrome. Conclusion: Metabolic syndrome in the non-pregnant state was associated with the development of preeclampsia. Further studies are needed to evaluate whether early intervention for metabolic syndrome before pregnancy can decrease the risk of developing preeclampsia. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Medical Science > 1. Journal Articles
Graduate School > Department of Biomedical Sciences > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Cho, Geum Joon photo

Cho, Geum Joon
의과대학 (의학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE