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Precision medicine for psychopharmacology: a general introduction

Authors
Shin, CheolminHan, ChangsuPae, Chi-UnPatkar, Ashwin A.
Issue Date
2016
Publisher
TAYLOR & FRANCIS LTD
Keywords
Precision medicine; personalized medicine; psychopharmacology; pharmacogenomics; pharmacometabolomics; exposomics; connectomics; big data; electronic health record; electronic medical record
Citation
EXPERT REVIEW OF NEUROTHERAPEUTICS, v.16, no.7, pp.831 - 839
Indexed
SCIE
SCOPUS
Journal Title
EXPERT REVIEW OF NEUROTHERAPEUTICS
Volume
16
Number
7
Start Page
831
End Page
839
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/90161
DOI
10.1080/14737175.2016.1182022
ISSN
1473-7175
Abstract
Introduction: Precision medicine is an emerging medical model that can provide accurate diagnoses and tailored therapeutic strategies for patients based on data pertaining to genes, microbiomes, environment, family history and lifestyle. Areas covered: Here, we provide basic information about precision medicine and newly introduced concepts, such as the precision medicine ecosystem and big data processing, and omics technologies including pharmacogenomics, pharamacometabolomics, pharmacoproteomics, pharmacoepigenomics, connectomics and exposomics. The authors review the current state of omics in psychiatry and the future direction of psychopharmacology as it moves towards precision medicine. Expert commentary: Advances in precision medicine have been facilitated by achievements in multiple fields, including large-scale biological databases, powerful methods for characterizing patients (such as genomics, proteomics, metabolomics, diverse cellular assays, and even social networks and mobile health technologies), and computer-based tools for analyzing large amounts of data.
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