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An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species
- Authors
- Fang, Chiew San; Oh, Kyung Hwan; Oh, Aram; Lee, Kwangyeol; Park, Seonhwa; Kim, Sinyoung; Park, Jin Kyoon; Yang, Haesik
- Issue Date
- 2016
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- CHEMICAL COMMUNICATIONS, v.52, no.34, pp.5884 - 5887
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMICAL COMMUNICATIONS
- Volume
- 52
- Number
- 34
- Start Page
- 5884
- End Page
- 5887
- ISSN
- 1359-7345
- Abstract
- This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR-and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.
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