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A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues

Authors
Lee, Yun HakTang, YongheVerwilst, PeterLin, WeiyingKim, Jong Seung
Issue Date
2016
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.52, no.75, pp.11247 - 11250
Indexed
SCIE
SCOPUS
Journal Title
CHEMICAL COMMUNICATIONS
Volume
52
Number
75
Start Page
11247
End Page
11250
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/90410
DOI
10.1039/c6cc06158c
ISSN
1359-7345
Abstract
A biotin appended formaldehyde sensor was found to specifically visualise both exogenous and endogenous levels of formaldehyde in biotin receptor positive cells over biotin negative cells by means of one-and two-photon excitation. The probe furthermore visualised endogenous levels of formaldehyde in tumour tissue slices up to 70 mu m depth.
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