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Rationally designed non-enzymatic fluorogenic 'turn-on' probe for uric acid

Authors
Pradhan, TuhinMaiti, SukhenduKumar, RajeshLee, Yun HakKim, Jong WanLee, Joung HaeKim, Jong Seung
Issue Date
10월-2015
Publisher
ELSEVIER SCI LTD
Keywords
Uric acid; Fluorescence; BODIPY; Non-enzymatic; PET; Hydrogen bonding
Citation
DYES AND PIGMENTS, v.121, pp.1 - 6
Indexed
SCIE
SCOPUS
Journal Title
DYES AND PIGMENTS
Volume
121
Start Page
1
End Page
6
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/92383
DOI
10.1016/j.dyepig.2015.05.001
ISSN
0143-7208
Abstract
The simple and cost-effective detection of uric acid in serum or urine is highly desirable as uric acid acts as a biomarker for various diseases. Herein, we report a rationally designed, non-enzymatic probe for the detection of uric acid in serum samples over a wide range of concentrations (lower: similar to 60 mu M, higher: similar to 700 mu M and normal: similar to 120-380 mu M) with 'turn-on' fluorogenic behaviour. (C) 2015 Elsevier Ltd. All rights reserved.
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