Rationally designed non-enzymatic fluorogenic 'turn-on' probe for uric acid
- Authors
- Pradhan, Tuhin; Maiti, Sukhendu; Kumar, Rajesh; Lee, Yun Hak; Kim, Jong Wan; Lee, Joung Hae; Kim, Jong Seung
- Issue Date
- 10월-2015
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Uric acid; Fluorescence; BODIPY; Non-enzymatic; PET; Hydrogen bonding
- Citation
- DYES AND PIGMENTS, v.121, pp.1 - 6
- Indexed
- SCIE
SCOPUS
- Journal Title
- DYES AND PIGMENTS
- Volume
- 121
- Start Page
- 1
- End Page
- 6
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/92383
- DOI
- 10.1016/j.dyepig.2015.05.001
- ISSN
- 0143-7208
- Abstract
- The simple and cost-effective detection of uric acid in serum or urine is highly desirable as uric acid acts as a biomarker for various diseases. Herein, we report a rationally designed, non-enzymatic probe for the detection of uric acid in serum samples over a wide range of concentrations (lower: similar to 60 mu M, higher: similar to 700 mu M and normal: similar to 120-380 mu M) with 'turn-on' fluorogenic behaviour. (C) 2015 Elsevier Ltd. All rights reserved.
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