Retreatment using a dual mode of low-fluence Q-switched and long-pulse Nd:YAG laser in patients with melasma aggravation after previous therapy
- Authors
- Choi, Chun Pil; Miyim, Seon; Seo, Soo Hong; Ahn, Hyo Hyun; Kye, Young Chul; Choi, Jae Eun
- Issue Date
- 6월-2015
- Publisher
- TAYLOR & FRANCIS INC
- Keywords
- Adverse events; long-pulsed Nd:YAG laser; melasma; Q-switched Nd:YAG laser; rebound hyperpigmentation
- Citation
- JOURNAL OF COSMETIC AND LASER THERAPY, v.17, no.3, pp.129 - 134
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF COSMETIC AND LASER THERAPY
- Volume
- 17
- Number
- 3
- Start Page
- 129
- End Page
- 134
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/93376
- DOI
- 10.3109/14764172.2014.988730
- ISSN
- 1476-4172
- Abstract
- Background: Aggravated melasma after treatment is vulnerable to stimulation, can easily deteriorate, and may be distressing without proper management. Objective: To retrospectively assess the effectiveness and safety of combination therapy using low-fluence Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser (QSNY) and long-pulse Nd:YAG laser (LPNY) (dual toning) in patients with rebound melasma. Materials and methods: A total of 30 patients with aggravated melasma after previous therapy who were treated with dual toning were enrolled. A total of 10 sessions were conducted at 1-week intervals, followed by maintenance treatment. The results were evaluated using the modified Melasma Area and Severity Index (mMASI) and the physician's global assessment (PGA) before and 2 months after completing the 10 treatment sessions. Results: The baseline mMASI was 10.48 +/- 3.64, which significantly decreased to 3.22 +/- 1.45 2 months after completing the 10 treatment sessions (p <0.001). Twenty-four patients (80%) had PGA grade 4 (76-100% improvement) and 6 patients (20%) had PGA grade 3 (51-75% improvement). Conclusion: Dual toning may be a safe and effective salvage treatment for patients with aggravated melasma after previous treatment. LPNY may stabilize melasma activity to prevent rebound hyperpigmentation via dermal remodeling.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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