A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd:YAG lasers in the treatment of nevus of Ota in Korean patients
- Authors
- Choi, Jae Eun; Lee, Joo Bong; Park, Ki Beom; Kim, Bang Soon; Yeo, Un-Cheol; Huh, Chang Hun; Kim, Jie Hoon; Kye, Young Chul
- Issue Date
- 6월-2015
- Publisher
- TAYLOR & FRANCIS LTD
- Keywords
- Nevus of Ota; Q-switched 755-nm Alexandrite laser; Q-switched 1064-nm neodymium: yttrium-aluminum-garnet laser
- Citation
- JOURNAL OF DERMATOLOGICAL TREATMENT, v.26, no.3, pp.240 - 245
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF DERMATOLOGICAL TREATMENT
- Volume
- 26
- Number
- 3
- Start Page
- 240
- End Page
- 245
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/93401
- DOI
- 10.3109/09546634.2014.930409
- ISSN
- 0954-6634
- Abstract
- Background: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium aluminum garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. Objective: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. Methods and materials: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0 J/cm(2), 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0 J/cm(2), 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. Results: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p = 0.026). Conclusion: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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