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Chronic Cavitary Pulmonary Histoplasmosis in a Non-HIV and Immunocompromised Patient without Overseas Travel History

Authors
Jung, Eun JuPark, Dae WonChoi, Jung-WooChoi, Won Suk
Issue Date
1-5월-2015
Publisher
YONSEI UNIV COLL MEDICINE
Keywords
Histoplasma capsulatum; immunocompromised host; Korea
Citation
YONSEI MEDICAL JOURNAL, v.56, no.3, pp.871 - 874
Indexed
SCIE
SCOPUS
KCI
Journal Title
YONSEI MEDICAL JOURNAL
Volume
56
Number
3
Start Page
871
End Page
874
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/93611
DOI
10.3349/ymj.2015.56.3.871
ISSN
0513-5796
Abstract
Korea is not known as an endemic area for Histoplasma. However, we experienced a case of histoplasmosis in a person who had never been abroad. A 65-year-old female was admitted to the hospital for evaluation of multiple lung nodules. A computed tomography (CT) scan of the chest showed multiple ill-defined consolidations and cavitations in all lobes of both lungs. The patient underwent a CT-guided lung biopsy, and a histopathology study showed findings compatible with histoplasmosis. Based on biopsy results and clinical findings, the patient was diagnosed with chronic cavitary pulmonary histoplasmosis. The patient recovered completely following itraconazole treatment. This is the first case report of pulmonary histoplasmosis unconnected with either HIV infection or endemicity in Korea.
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