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Highly Selective In Vivo Imaging of Endogenous/Exogenous Phosphate Ion over ATP and PPi
- Authors
- Zhang, Jun Feng; Guo, Lin E.; Zang, Tie Nan; Duan, Yu Lian; Liu, Xin Yi; Yang, Zhigang; Verwilst, Peter; Luo, Kaijun; Wang, Guang Ke; Kou, Jun Feng; Zhou, Ying; Kim, Jong Seung
- Issue Date
- 5월-2015
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- 1; 8-naphthalene imide; fluorescent probes; in vivo imaging; inorganic phosphate; sensors
- Citation
- CHEMISTRY-AN ASIAN JOURNAL, v.10, no.5, pp.1165 - 1169
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMISTRY-AN ASIAN JOURNAL
- Volume
- 10
- Number
- 5
- Start Page
- 1165
- End Page
- 1169
- ISSN
- 1861-4728
- Abstract
- A chemodosimeter was designed to function as a highly selective phosphate ion (P-i) sensor, showing a 91-fold ratiometric fluorescence enhancement. The probe successfully visualized exogenous and endogenous apyrase-catalyzed P-i generation and was the first probe able to trace the generation and enrichment of P-i through hemichannel closure in Sf9 cells.
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