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A Fluorescent Chemosensor for Hg2+ and Cd2+ Ions in Aqueous Medium under Physiological pH and Its Applications in Imaging Living Cells
- Issue Date
- 20-4월-2015
- Publisher
- AMER CHEMICAL SOC
- Citation
- INORGANIC CHEMISTRY, v.54, no.8, pp.3929 - 3936
- Indexed
- SCIE
SCOPUS
- Journal Title
- INORGANIC CHEMISTRY
- Volume
- 54
- Number
- 8
- Start Page
- 3929
- End Page
- 3936
- ISSN
- 0020-1669
- Abstract
- A new BODIPY derivative with 2,2'-(ethane-1,2-diylbis(oxy))bis(N,N-bis(pyridine-2-ylmethyl)aniline unit as the metal receptor has been designed and synthesized. The dye selectively detects either Cd2+ or Hg2+ ions in the presence of hosts of other biologically important and environmentally relevant metal ions in aqueous medium at physiological pH. Binding of metal ions causes a change in the emission behavior of the dye from weakly fluorescent to highly fluorescent. Confocal microscopic experiments validate that the dye can be used to identify changes in either Hg2+ or Cd2+ levels in living cells.
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