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Isoflavones with neuroprotective activities from fruits of Cudrania tricuspidata

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dc.contributor.authorNguyen Tuan Hiep-
dc.contributor.authorKwon, Jaeyoung-
dc.contributor.authorKim, Dong-Woo-
dc.contributor.authorHwang, Bang Yeon-
dc.contributor.authorLee, Hak-Ju-
dc.contributor.authorMar, Woongchon-
dc.contributor.authorLee, Dongho-
dc.date.accessioned2021-09-04T18:32:12Z-
dc.date.available2021-09-04T18:32:12Z-
dc.date.created2021-06-15-
dc.date.issued2015-03-
dc.identifier.issn0031-9422-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/94202-
dc.description.abstractTen isoflavones, cudraisoflavones B-K (1-10), together with 27 known isoflavones, were isolated from the EtOAc soluble extract of fruits of Cudrania tricuspidata. The structures of compounds 1-10 were elucidated on the basis of MS and NMR spectroscopic data, including 2D NMR experiments. Compounds 7-9 and three known (11-13) compounds showed neuroprotective activity against 6-hydroxydopamine induced cell death in human neuroblastoma SH-SY5Y cells, with EC50 values of 0.5-9.2 mu M. (C) 2014 Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectROOT BARK-
dc.subjectFLEMINGIA-PHILIPPINENSIS-
dc.subjectPRENYLATED ISOFLAVONOIDS-
dc.subjectISOPRENYLATED XANTHONES-
dc.subjectFLAVONOIDS-
dc.subjectERYTHRINA-
dc.subjectCONSTITUENTS-
dc.subjectCOMPONENTS-
dc.subjectCYTOTOXICITY-
dc.subjectTHONNINGII-
dc.titleIsoflavones with neuroprotective activities from fruits of Cudrania tricuspidata-
dc.typeArticle-
dc.contributor.affiliatedAuthorLee, Dongho-
dc.identifier.doi10.1016/j.phytochem.2014.10.021-
dc.identifier.scopusid2-s2.0-84922756688-
dc.identifier.wosid000350527400017-
dc.identifier.bibliographicCitationPHYTOCHEMISTRY, v.111, pp.141 - 148-
dc.relation.isPartOfPHYTOCHEMISTRY-
dc.citation.titlePHYTOCHEMISTRY-
dc.citation.volume111-
dc.citation.startPage141-
dc.citation.endPage148-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaPlant Sciences-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryPlant Sciences-
dc.subject.keywordPlusROOT BARK-
dc.subject.keywordPlusFLEMINGIA-PHILIPPINENSIS-
dc.subject.keywordPlusPRENYLATED ISOFLAVONOIDS-
dc.subject.keywordPlusISOPRENYLATED XANTHONES-
dc.subject.keywordPlusFLAVONOIDS-
dc.subject.keywordPlusERYTHRINA-
dc.subject.keywordPlusCONSTITUENTS-
dc.subject.keywordPlusCOMPONENTS-
dc.subject.keywordPlusCYTOTOXICITY-
dc.subject.keywordPlusTHONNINGII-
dc.subject.keywordAuthorCudrania tricuspidata-
dc.subject.keywordAuthorMoraceae-
dc.subject.keywordAuthorIsoflavones-
dc.subject.keywordAuthorNeuroprotection-
dc.subject.keywordAuthorParkinson&apos-
dc.subject.keywordAuthors disease-
dc.subject.keywordAuthor6-OHDA-
dc.subject.keywordAuthorHuman neuroblastoma SH-SY5Y-
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