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Seasonality of Gout in Korea: A Multicenter Study

Authors
Choi, Hyo JinLee, Chan HeeLee, Joo HyunYoon, Bo YoungKim, Hyoun AhSuh, Chang HeeChoi, Sang TaeSong, Jung SooJoo, HoYeonChoi, Sung JaeLee, Ji SooShin, KiChulJun, Jae-BumBaek, Han Joo
Issue Date
3월-2015
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
Gout Onset; Flares; Seasonality; Summer; Korea
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.30, no.3, pp.240 - 244
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
30
Number
3
Start Page
240
End Page
244
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/94213
DOI
10.3346/jkms.2015.30.3.240
ISSN
1011-8934
Abstract
The object of this study was to evaluate the seasonality of gout in Korea. We retrospectively examined data from 330 patients seen at nine rheumatology clinics, treated with urate lowering therapy (ULT) more than one year after stopping prophylactic medication. Demographic data, clinical and laboratory features, and seasonality of gout onset and flares were collected. Season was classified in three- month intervals. The mean age was 52.2 yr and mean disease duration was 26.8 months. The male to female count was 318:12. The onset of acute gouty attacks was obtained in 256 patients. Gout developed most commonly in summer season (36.7%) (P < 0.001) and in June (15.6%, P = 0.002). During ULT, there were 147 (male 97.3%) gout flares. Although there was no statistically significant difference, gout flares were more common in summer (30.6%). Aggravating factors were identified in 57 flares: alcohol (72.0%) was most common. In the patients who attained target serum uric acid (< 6 mg/dL) at the end of prophylaxis, gout flares were high in fall (35.8%) and September (17.0%). In Korea, the summer is most common season of gout onset and there is a tendency for gout flares to increase during ULT in summer/fall season.
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