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Biotin-guided anticancer drug delivery with acidity-triggered drug release

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dc.contributor.authorPark, Soyeon-
dc.contributor.authorKim, Eunjin-
dc.contributor.authorKim, Won Young-
dc.contributor.authorKang, Chulhun-
dc.contributor.authorKim, Jong Seung-
dc.date.accessioned2021-09-05T00:52:32Z-
dc.date.available2021-09-05T00:52:32Z-
dc.date.created2021-06-15-
dc.date.issued2015-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/96181-
dc.description.abstractA novel biotin-guided anticancer drug delivery system, prodrug 9, consisting of biotin, nitrobenzene, and doxorubicin, with acid-triggered drug releasing capability was synthesized. Its cellular uptake and anticancer activity are selective to the HepG2 cell line over the WI-38 cell line, as revealed by fluorescence confocal microscopic experiments and MTT assay.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectMESOPOROUS SILICA NANOPARTICLES-
dc.subjectPH-
dc.subjectPRODRUG-
dc.subjectTUMORS-
dc.titleBiotin-guided anticancer drug delivery with acidity-triggered drug release-
dc.typeArticle-
dc.contributor.affiliatedAuthorKim, Jong Seung-
dc.identifier.doi10.1039/c5cc03003j-
dc.identifier.scopusid2-s2.0-84930211772-
dc.identifier.wosid000354997400025-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.51, no.45, pp.9343 - 9345-
dc.relation.isPartOfCHEMICAL COMMUNICATIONS-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume51-
dc.citation.number45-
dc.citation.startPage9343-
dc.citation.endPage9345-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusMESOPOROUS SILICA NANOPARTICLES-
dc.subject.keywordPlusPH-
dc.subject.keywordPlusPRODRUG-
dc.subject.keywordPlusTUMORS-
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