A novel reflectance-based aptasensor using gold nanoparticles for the detection of oxytetracycline
- Authors
- Seo, Ho Bin; Kwon, Young Seop; Lee, Ji-eun; Cullen, David; Noh, Hongseok (Moses); Gu, Man Bock
- Issue Date
- 2015
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- ANALYST, v.140, no.19, pp.6671 - 6675
- Indexed
- SCIE
SCOPUS
- Journal Title
- ANALYST
- Volume
- 140
- Number
- 19
- Start Page
- 6671
- End Page
- 6675
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/96192
- DOI
- 10.1039/c5an00726g
- ISSN
- 0003-2654
- Abstract
- We present a novel reflectance-based colorimetric aptasensor using gold nanoparticles for the detection of oxytetracycline for the first time. It was found that the reflectance-based measurement at two wavelengths (650 and 520 nm) can generate more stable and sensitive signals than absorbance-based sensors to determine the aggregation of AuNPs, even at high AuNP concentrations. One of the most common antibacterial agents, oxytetracycline (OTC), was detected at concentrations as low as 1 nM in both buffer solution and tap water, which was 25-fold more sensitive, compared to the previous absorbance-based colorimetric aptasensors. This reflectance-based colorimetric aptasensor using gold nanoparticles is considered to be a better platform for portable sensing of small molecules using aptamers.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Biotechnology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.