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Highly-efficient T4 DNA ligase-based SNP analysis using a ligation fragment containing a modified nucleobase at the end

Authors
Jang, Eui KyoungYang, MunheePack, Seung Pil
Issue Date
2015
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.51, no.66, pp.13090 - 13093
Indexed
SCIE
SCOPUS
Journal Title
CHEMICAL COMMUNICATIONS
Volume
51
Number
66
Start Page
13090
End Page
13093
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/96197
DOI
10.1039/c5cc03761a
ISSN
1359-7345
Abstract
A highly accurate ligase-based SNP analysis was developed by using modified base-end downstream ligation fragments as detection probes, which can clearly distinguish C/T SNP types without any "false-positive'' results.
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