Characteristics of platelet indices, neutrophil-to-lymphocyte ratio and erythrocyte sedimentation rate compared with C reactive protein in patients with cerebral infarction: a retrospective analysis of comparing haematological parameters and C reactive protein
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Jong-Han | - |
dc.contributor.author | Kwon, Kyum-Yil | - |
dc.contributor.author | Yoon, Soo-Young | - |
dc.contributor.author | Kim, Hyon-Suk | - |
dc.contributor.author | Lim, Chae Seung | - |
dc.date.accessioned | 2021-09-05T03:19:37Z | - |
dc.date.available | 2021-09-05T03:19:37Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-11 | - |
dc.identifier.issn | 2044-6055 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/96856 | - |
dc.description.abstract | Objective: Elevation of C reactive protein (CRP) is one of the major acute-phase responses following ischaemic or haemorrhagic stroke. This study aims to investigate the associations between platelet indices, neutrophil-to-lymphocyte ratio (NLR) and erythrocyte sedimentation rate (ESR) compared with CRP in patients with cerebral infarction. Setting: The clinical data of patients with cerebral infarction were analysed retrospectively. Participants: We analysed, unduplicated, 516 patients with cerebral infarction (mean age 66.2 +/- 12.7, male/female=291/225). Outcome measures: Mean platelet volume (MPV), MPV to platelet count, NLR and ESR were compared with CRP in patients with cerebral infarction in a single institute through Spearman correlation test. Results: There were significant correlations between CRP and MPV (rho=0.088, p=0.045), NLR (rho=0.4, p<0.001) and ESR (rho=0.468, p<0.001) in patients with cerebral infarction. In the male group, NLR (rho=0.398, p<0.001) and ESR (rho=0.502, p<0.001) showed significant correlations with CRP. In the female group, CRP showed significant correlations with MPV (rho=0.17, p=0.011), NLR (rho=0.392, p<0.001) and ESR (rho=0.475, p<0.001). Conclusions: MPV, NLR and ESR showed significant correlation with CRP in patients with cerebral infarction. MPV and NLR are cost-effective and simple parameters that can be attainable by using an automatic haematology analyser. Further well-designed and large-scale prospective studies are warranted to evaluate platelet indices or NLR for monitoring patients with cerebral infarction. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | BMJ PUBLISHING GROUP | - |
dc.title | Characteristics of platelet indices, neutrophil-to-lymphocyte ratio and erythrocyte sedimentation rate compared with C reactive protein in patients with cerebral infarction: a retrospective analysis of comparing haematological parameters and C reactive protein | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoon, Soo-Young | - |
dc.contributor.affiliatedAuthor | Lim, Chae Seung | - |
dc.identifier.doi | 10.1136/bmjopen-2014-006275 | - |
dc.identifier.scopusid | 2-s2.0-84911948456 | - |
dc.identifier.wosid | 000209949200001 | - |
dc.identifier.bibliographicCitation | BMJ OPEN, v.4, no.11 | - |
dc.relation.isPartOf | BMJ OPEN | - |
dc.citation.title | BMJ OPEN | - |
dc.citation.volume | 4 | - |
dc.citation.number | 11 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.