Escitalopram Efficacy in Depression A Cross-Ethnicity Examination of the Serotonin Transporter Promoter Polymorphism
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bousman, Chad A. | - |
dc.contributor.author | Sarris, Jerome | - |
dc.contributor.author | Won, Eun-Soo | - |
dc.contributor.author | Chang, Hun-Soo | - |
dc.contributor.author | Singh, Ajeet | - |
dc.contributor.author | Lee, Hwa-Young | - |
dc.contributor.author | Ham, Byung-Joo | - |
dc.contributor.author | Tan, Chay-Hoon | - |
dc.contributor.author | Lee, Min-Soo | - |
dc.contributor.author | Ng, Chee H. | - |
dc.date.accessioned | 2021-09-05T04:53:12Z | - |
dc.date.available | 2021-09-05T04:53:12Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-10 | - |
dc.identifier.issn | 0271-0749 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/97324 | - |
dc.description.abstract | Current evidence suggests that polymorphism in the serotonin transporter gene (5-HTTLPR) predicts antidepressant efficacy in whites but less so in Asians. However, it is not clear whether this effect can be observed for specific types of antidepressant drugs. White (n = 47) and Korean (n = 118) participants with major depressive disorder were treated with escitalopram and assessed over 8 weeks. Among those with the l/l but not l/s or s/s genotypes, whites had greater depression score reductions, response rates, and remission rates compared with Koreans. Our results suggest that 5-HTTLPR predicts escitalopram efficacy in an ethnicity-dependent manner. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | REUPTAKE INHIBITORS | - |
dc.subject | TREATMENT RESPONSE | - |
dc.subject | MAJOR DEPRESSION | - |
dc.subject | GENE | - |
dc.subject | DISORDER | - |
dc.subject | ASSOCIATION | - |
dc.subject | METAANALYSIS | - |
dc.subject | MODERATION | - |
dc.subject | EXPRESSION | - |
dc.title | Escitalopram Efficacy in Depression A Cross-Ethnicity Examination of the Serotonin Transporter Promoter Polymorphism | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ham, Byung-Joo | - |
dc.contributor.affiliatedAuthor | Lee, Min-Soo | - |
dc.identifier.doi | 10.1097/JCP.0000000000000165 | - |
dc.identifier.scopusid | 2-s2.0-84907423655 | - |
dc.identifier.wosid | 000341809700021 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, v.34, no.5, pp.645 - 648 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY | - |
dc.citation.title | JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY | - |
dc.citation.volume | 34 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 645 | - |
dc.citation.endPage | 648 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.subject.keywordPlus | REUPTAKE INHIBITORS | - |
dc.subject.keywordPlus | TREATMENT RESPONSE | - |
dc.subject.keywordPlus | MAJOR DEPRESSION | - |
dc.subject.keywordPlus | GENE | - |
dc.subject.keywordPlus | DISORDER | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | MODERATION | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordAuthor | antidepressant | - |
dc.subject.keywordAuthor | genotype | - |
dc.subject.keywordAuthor | pharmacogenetic | - |
dc.subject.keywordAuthor | efficacy | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.