Imaging Features of Growing Teratoma Syndrome Following a Malignant Ovarian Germ Cell Tumor
- Authors
- Han, Na Yeon; Sung, Deuk Jae; Park, Beom Jin; Kim, Min Ju; Cho, Sung Bum; Kim, Kyeong Ah; Song, Jae Yun
- Issue Date
- 7월-2014
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Keywords
- ovarian neoplasms; germ cell tumors; adjuvant chemotherapy; multidetector computed tomography; neoplastic processes
- Citation
- JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, v.38, no.4, pp.551 - 557
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
- Volume
- 38
- Number
- 4
- Start Page
- 551
- End Page
- 557
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/98112
- DOI
- 10.1097/RCT.0000000000000073
- ISSN
- 0363-8715
- Abstract
- Objective: To access imaging findings of growing teratoma syndrome (GTS), which is a rare complication of malignant ovarian germ cell tumor (GCT) after chemotherapy. Methods: Five patients met the criteria for GTS. Computed tomography and magnetic resonance images were retrospectively reviewed by 2 radiologists in consensus for margin, attenuation, and the presence of gross fat or calcification of GTS lesions, which were compared with primary GCTs regarding tumor composition. Results: Growing teratoma syndrome lesions were characterized as follows: poorly circumscribed, diffuse peritoneal masses in 2 patients; well-circumscribed, localized peritoneal masses in 1 patient, and ovarian masses in 2 patients. Features more noticeable in GTS lesions were more prominent fatty components in 4 patients and purely cystic lesion in 1 patient. Conclusions: Growing teratoma syndrome can be manifested as intraperitoneal masses with an increased fatty or cystic component. Radiologists should consider GTS when there are such masses on follow-up imaging studies in patients with malignant ovarian GCT.
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