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Evaluation of McDonald MRI criteria for dissemination in space in Korean patients with clinically isolated syndromes
- Authors
- Huh, So-Young; Kim, Su-Hyun; Kim, Woojun; Lee, Sang-Hyun; Park, Min Su; Ahn, Suk-Won; Kim, Byung-Jo; Cho, Joong-Yang; Kim, Ho Jin
- Issue Date
- 4월-2014
- Publisher
- SAGE PUBLICATIONS LTD
- Keywords
- Multiple sclerosis; MRI
- Citation
- MULTIPLE SCLEROSIS JOURNAL, v.20, no.4, pp.492 - 495
- Indexed
- SCIE
SCOPUS
- Journal Title
- MULTIPLE SCLEROSIS JOURNAL
- Volume
- 20
- Number
- 4
- Start Page
- 492
- End Page
- 495
- ISSN
- 1352-4585
- Abstract
- We investigated the validity of the 2005 and 2010 McDonald magnetic resonance imaging (MRI) criteria for dissemination in space (DIS) to predict the conversion of clinically definite multiple sclerosis (CDMS) in 94 Korean patients with clinically isolated syndromes (CIS). The sensitivity, specificity, accuracy, positive and negative predictive values of the 2005, 2010 McDonald DIS criteria were comparable to those observed in the Caucasian population. This finding suggests that after careful exclusion of alternative explanations, particularly neuromyelitis optica (NMO) and NMO spectrum disorder (NMOSD), both the 2005 and 2010 McDonald DIS criteria are also useful to predict conversion to CDMS in Korean patients with CIS.
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