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Incremental Learning With Selective Memory (ILSM): Towards Fast Prostate Localization for Image Guided Radiotherapy

Authors
Gao, YaozongZhan, YiqiangShen, Dinggang
Issue Date
2월-2014
Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
Keywords
Anatomy detection; image-guided radiotherapy (IGRT); incremental learning; machine learning; prostate segmentation
Citation
IEEE TRANSACTIONS ON MEDICAL IMAGING, v.33, no.2, pp.518 - 534
Indexed
SCIE
SCOPUS
Journal Title
IEEE TRANSACTIONS ON MEDICAL IMAGING
Volume
33
Number
2
Start Page
518
End Page
534
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/99431
DOI
10.1109/TMI.2013.2291495
ISSN
0278-0062
Abstract
Image-guided radiotherapy (IGRT) requires fast and accurate localization of the prostate in 3-D treatment-guided radiotherapy, which is challenging due to low tissue contrast and large anatomical variation across patients. On the other hand, the IGRT workflow involves collecting a series of computed tomography (CT) images from the same patient under treatment. These images contain valuable patient-specific information yet are often neglected by previous works. In this paper, we propose a novel learning framework, namely incremental learning with selective memory (ILSM), to effectively learn the patient-specific appearance characteristics from these patient-specific images. Specifically, starting with a population-based discriminative appearance model, ILSM aims to "personalize" the model to fit patient-specific appearance characteristics. The model is personalized with two steps: backward pruning that discards obsolete population-based knowledge and forward learning that incorporates patient-specific characteristics. By effectively combining the patient-specific characteristics with the general population statistics, the incrementally learned appearance model can localize the prostate of a specific patient much more accurately. This work has three contributions: 1) the proposed incremental learning framework can capture patient-specific characteristics more effectively, compared to traditional learning schemes, such as pure patient-specific learning, population-based learning, and mixture learning with patient-specific and population data; 2) this learning framework does not have any parametric model assumption, hence, allowing the adoption of any discriminative classifier; and 3) using ILSM, we can localize the prostate in treatment CTs accurately (DSC similar to 0.89) and fast (similar to 4 s), which satisfies the real-world clinical requirements of IGRT.
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