Impact of Atherosclerosis Detection by Carotid Ultrasound on Physician Behavior and Risk-Factor Management in Asymptomatic Hypertensive Subjects
- Authors
- Hong, Sung-Jin; Chang, Hyuk-Jae; Song, Kijun; Hong, Geu-Ru; Park, Seung Woo; Kang, Hyun-Jae; Kim, Eung Ju; Kim, Dong-Soo; Jeong, Myung-Ho
- Issue Date
- Feb-2014
- Publisher
- WILEY
- Citation
- CLINICAL CARDIOLOGY, v.37, no.2, pp.91 - 96
- Indexed
- SCIE
SCOPUS
- Journal Title
- CLINICAL CARDIOLOGY
- Volume
- 37
- Number
- 2
- Start Page
- 91
- End Page
- 96
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/99439
- DOI
- 10.1002/clc.22220
- ISSN
- 0160-9289
- Abstract
- Background There are limited data regarding the impact of atherosclerosis detection by carotid ultrasound (CUS) on physician prevention efforts and risk-factor management for cardiovascular disease. Hypothesis Atherosclerosis detection by CUS in asymptomatic hypertensive patients would lead to physician prevention efforts, including target low-density lipoprotein cholesterol (LDL-C) level and prescription. Also, it may improve risk-factor management. Methods A total of 347 asymptomatic hypertensive subjects (age 61 8 years, 189 men) were prospectively recruited from 22 hospitals. Prior to CUS, physicians were surveyed regarding target LDL-C level. After CUS, patients were classified into positive CUS (n = 182) and negative CUS (n = 165) groups based on CUS results. Physicians were resurveyed to assess whether the initial target LDL-C goals were changed. At 6 months, cardiovascular risk-factor modification status was reassessed. Results The proportion of lowered target LDL-C levels was significantly larger in the positive CUS group than in the negative CUS group (52% vs 23%, P < 0.001). These results were observed even in subjects who had low and moderate risk according to National Cholesterol Education Program-Adult Treatment Panel III guidelines. Lipid-lowering agents were similarly added or switched to another class in both groups (7% in the positive CUS group vs 11% in the negative CUS group, P = 0.153). LDL-C was significantly decreased in the positive CUS group ( = -24 +/- 38 mg/dL, P < 0.001), whereas it was not significantly decreased in the negative CUS group ( = -6 +/- 31 mg/dL, P = 0.105). Conclusions Atherosclerosis detection by CUS lowered physicians' target LDL-C level and improved cardiovascular risk management in terms of LDL-C reduction.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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