L-Ascorbic Acid Addition to Chitosan Reduces Body Weight in Overweight Women
- Authors
- Jung, Eun Young; Jun, Sung Chul; Chang, Un Jae; Suh, Hyung Joo
- Issue Date
- 2014
- Publisher
- VERLAG HANS HUBER
- Keywords
- L-ascorbic acid; chitosan; dietary supplements; obesity; weight loss
- Citation
- INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH, v.84, no.1-2, pp.5 - 11
- Indexed
- SCIE
SCOPUS
- Journal Title
- INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
- Volume
- 84
- Number
- 1-2
- Start Page
- 5
- End Page
- 11
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/101219
- DOI
- 10.1024/0300-9831/a000187
- ISSN
- 0300-9831
- Abstract
- Previously, we have found that the addition of L-ascorbic acid to chitosan enhanced the reduction in body weight gain in guinea pigs fed a high-fat diet. We hypothesized that the addition of L-ascorbic acid to chitosan would accelerate the reduction of body weight in humans, similar to the animal model. Overweight subjects administered chitosan with or without L-ascorbic acid for 8 weeks, were assigned to three groups: Control group (N = 26, placebo, vehicle only), Chito group (N = 27, 3 g/day chitosan), and Chito-vita group (N = 27,3 g/day chitosan plus 2 g/day L-ascorbic acid). The body weights and body mass index (BMI) of the Chito and Chito-vita groups decreased significantly (p < 0.05) compared to the Control group. The BMI of the Chito-vita group decreased significantly compared to the Chito group (Chito: -1.0 kg/m(2) vs. Chito-vita: -1.6 kg/m(2), p < 0.05). The results showed that the chitosan enhanced reduction of body weight and BMI was accentuated by the addition of L-ascorbic acid. The fat mass, percentage body fat, body circumference, and skinfold thickness in the Chito and Chito-vita groups decreased more than the Control group; however, these parameters were not significantly different between the three groups. Chitosan combined with L-ascorbic acid may be useful for controlling body weight.
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Collections - College of Health Sciences > School of Biosystems and Biomedical Sciences > 1. Journal Articles
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