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Implementation of a Biocircuit Implants for Neurotransmitter Release During Neuro-Stimulation
- Authors
- Ly, Suw Young; Choi, Dal Woong
- Issue Date
- 8월-2013
- Publisher
- BENTHAM SCIENCE PUBL LTD
- Keywords
- neuro sens; electrochemical; brain; in vivo; interface; Epinephrine
- Citation
- CURRENT NEUROVASCULAR RESEARCH, v.10, no.3, pp.238 - 246
- Indexed
- SCIE
SCOPUS
- Journal Title
- CURRENT NEUROVASCULAR RESEARCH
- Volume
- 10
- Number
- 3
- Start Page
- 238
- End Page
- 246
- ISSN
- 1567-2026
- Abstract
- Neurotransmitter assay of epinephrine (EP) was sought using a modified carbon nanotube paste electrode (PE). Using optimum conditions, cyclic voltammetry (CV) and the square wave (SW) stripping voltammetric working ranges were attained to 10-100 mgL(-1) (CV) and 20-140 ngL(-1) (SW). The relative standard deviation of 0.0549 (n = 15) was obtained at 20.0 mgL(-1) EP constant. Here, the analytical detection limit (S/N) was reached with 4.60 ngL(-1) (2.5x10(-11) molL(-1)) EP. The hand-made electrode was implanted into the in-vivo brain core of the animals and was used in chronoamperometric neuro detection. The results obtained are applicable in neuro sensing, physiological control, and other neuroscience fields.
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