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Hemorheological changes caused by lead exposure
- Authors
- Kim, C. B.; Shin, Sehyun; Song, Seok-Heung
- Issue Date
- 2013
- Publisher
- IOS PRESS
- Keywords
- Lead; toxicology; hemorheology; deformability; aggregation
- Citation
- CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, v.55, no.3, pp.341 - 348
- Indexed
- SCIE
SCOPUS
- Journal Title
- CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
- Volume
- 55
- Number
- 3
- Start Page
- 341
- End Page
- 348
- ISSN
- 1386-0291
- Abstract
- Lead is a ubiquitous, biohazardous, and toxic heavy metal that induces a broad range of physiological, biochemical, and behavioral dysfunctions. We investigated the effect of lead on hemorheological characteristics, including deformability and aggregation. We found that red blood cell (RBC) deformability was unaffected at low concentrations of lead-rich plasma, but showed a significant decrease at high concentrations even within 1 h of incubation. In addition, apparent alterations in RBC aggregation were observed with an increase in lead concentration and incubation time. These results highlight the influence of lead on hemorheology and microcirculation.
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Collections - College of Engineering > Department of Mechanical Engineering > 1. Journal Articles
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