동맥 스핀 라벨링 자기공명영상의 펄스 관류 신호의 시뮬레이션Simulations of Perfusion Signals of Pulsed Arterial Spin Labeling MRI
- Other Titles
- Simulations of Perfusion Signals of Pulsed Arterial Spin Labeling MRI
- Authors
- 김혁기; 장건호; 오창현
- Issue Date
- 2011
- Publisher
- 대한자기공명의과학회
- Keywords
- Perfusion; arterial spin labeling; Bloch equation; cerebral blood flow
- Citation
- Investigative Magnetic Resonance Imaging, v.15, no.3, pp.191 - 199
- Indexed
- KCI
- Journal Title
- Investigative Magnetic Resonance Imaging
- Volume
- 15
- Number
- 3
- Start Page
- 191
- End Page
- 199
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/113842
- ISSN
- 2384-1095
- Abstract
- Purpose: A pulsed arterial spin labeling (PASL) signal usually depends on several parameters. The objective of this study was to determine the optimal parameters using simulation for perfusion signals of PASL magnetic resonance imaging (MRI).
Materials and methods: Perfusion signals, ΔM/M_(0b), derived from the Bloch equation were evaluated in regard to the four most important parameters in PASL MRI: the tissue-to-blood coefficient (λ), the longitudinal relaxation time of blood (T_(1b)), the arterial transit delay from the application of tag (δt), and the magnetic field strength (B0). The simulation was conducted with Mathematica software.
Results: First, perfusion signals differed depending on the value of λ in brain tissue. The maximum signal, ΔM/M_(0b) = 0.390, was obtained at an inversion time (TI) = 1.53 sec for gray matter on 3T MRI. Second, perfusion signals were reduced with increasing δt. The maximum signal, ΔM/M0b = 0.526, was obtained at TI = 2.1 sec for δt = 0.5 sec. Finally, perfusion signals increased with increasing B0. The maximum signal, ΔM = 1.15, was obtained at TI = 1.52 sec for 3T MRI.
Conclusion: We reported that the optimized TI values were obtained to provide the highest PASL signals. It is very important that optimized TI values be used to obtain high-quality perfusion signals using PASL MRI.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Electronics and Information Engineering > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.