영지의 액체배양 중 균사형태에 미치는 통기 · 교반의 영향 및 Scale-upEffect of Agitation, Aeration and Scale-up on Mycelial Morphology During Liquid Culture of Ganoderma lucidum
- Other Titles
- Effect of Agitation, Aeration and Scale-up on Mycelial Morphology During Liquid Culture of Ganoderma lucidum
- Authors
- 이학수; 이기영; 최상윤; 이신영
- Issue Date
- 2011
- Publisher
- 한국생물공학회
- Keywords
- Ganoderma lucidum; scale-up; morphology; liquid culture; regression analysis; bi-staged pH process
- Citation
- KSBB Journal, v.26, no.4, pp.357 - 364
- Indexed
- KCI
- Journal Title
- KSBB Journal
- Volume
- 26
- Number
- 4
- Start Page
- 357
- End Page
- 364
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/114565
- ISSN
- 1225-7117
- Abstract
- This study was carried out to investigate the effects of agitation, aeration and scale-up on the mycelial growth,exo-polysaccharide (EPS) production, and mycelial morphology in the liquid culture of Ganoderma lucidum. A correlation between roughness and operating variables was also studied to scale-up the liquid culture of G. lucidum in a jar fermenter.
When the agitation speed or aeration rate increased, the morphological form was changed from rough pellet to smooth pellet form. Increase of the agitation and aeration reduced the mycelial roughness. On the other hand, in the case of pellet size, it was not affected by aeration. The higher EPS production was obtained at approximately 17% of roughness and mycelial pellet size of 3~5 mm. The morphology at each fermenter was closely correlated with kLa value, and it was found that similarity of morphology would be used as a criteria of scale-up for liquid culture of G. lucidum.
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Collections - College of Life Sciences and Biotechnology > Division of Life Sciences > 1. Journal Articles
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