Vitamin C Increases the Fecal Fat Excretion by Chitosan in Guinea-pigs, Thereby Reducing Body Weight Gain
- Authors
- Jun, S. C.; Jung, E. Y.; Kang, D. H.; Kim, J. M.; Chang, U. J.; Suh, H. J.
- Issue Date
- 8월-2010
- Publisher
- WILEY
- Keywords
- vitamin C; chitosan; guinea-pig; antiobesity; fecal excretion
- Citation
- PHYTOTHERAPY RESEARCH, v.24, no.8, pp.1234 - 1241
- Indexed
- SCIE
SCOPUS
- Journal Title
- PHYTOTHERAPY RESEARCH
- Volume
- 24
- Number
- 8
- Start Page
- 1234
- End Page
- 1241
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/115968
- DOI
- 10.1002/ptr.2970
- ISSN
- 0951-418X
- Abstract
- The aims of this study were to investigate the antiobesity properties of chitosan on its own, as well as in the presence of vitamin C, in vivo. Hartley guinea-pigs were divided into Control (normal diet), F-control (high fat diet), Chitosan (high fat diet with 5.0% chitosan) and Chito-vit C (high fat diet with 5.0% chitosan containing 0.5% vitamin C) groups, respectively. The effects of chitosan, both alone and in the presence of vitamin C. on body weight, total fecal weight, fecal composition and plasma lipid level were studied for 5 weeks. The results of this study indicated that the fat-binding and water-holding capacity of chitosan might decrease body weight by reducing the absorption of cholesterol and fat, subsequently increasing total fecal weight, fecal fat excretion and fecal water excretion. Vitamin C increased the fecal fat excretion by chitosan in guinea-pigs, thereby reducing body weight gain. Copyright (C) 2010 John Wiley & Sons, Ltd.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Health Sciences > School of Biosystems and Biomedical Sciences > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.