Proteomic analysis of endogenous conjugated linoleic acid biosynthesis in lactating rats and mouse mammary gland epithelia cells (HC11)
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jin, Yong-Cheng | - |
dc.contributor.author | Lee, Hong-Gu | - |
dc.contributor.author | Xu, Cheng-Xiong | - |
dc.contributor.author | Han, Jeng-A | - |
dc.contributor.author | Choi, Seong-Ho | - |
dc.contributor.author | Song, Man-Kang | - |
dc.contributor.author | Kim, Young-Jun | - |
dc.contributor.author | Lee, Ki-Beom | - |
dc.contributor.author | Kim, Seon-Ku | - |
dc.contributor.author | Kang, Han-Seok | - |
dc.contributor.author | Cho, Byung-Wook | - |
dc.contributor.author | Shin, Teak-Soon | - |
dc.contributor.author | Choi, Yun-Jaie | - |
dc.date.accessioned | 2021-09-08T04:06:48Z | - |
dc.date.available | 2021-09-08T04:06:48Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010-04 | - |
dc.identifier.issn | 1570-9639 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/116693 | - |
dc.description.abstract | This study was conducted to investigate the amount of CLA synthesized endogenously by rat mammary tissues in response to TVA (a precursor for cis-9, trans-11 CIA endogenous synthesis) treatment as well as the differences in the protein expression of genes encoding the biosynthesis of CLA in rat mammary tissue and mouse mammary gland epithelia cells (HC11). Treatment with TVA resulted in improved CIA productivity. Furthermore, 2-DE revealed two spots in samples of mammary tissues and one spot in samples of mammary gland epithelia cells (HC11) that were consistently altered in the TVA treatment groups when compared with the control group (non-fatty acid). The mRNA expression patterns of three of the proteins (PD1, PRDX2, LAMR1), as measured by real-time PCR, were similar to the pattern of protein abundance. In addition, the expression of SCID mRNA in the mammary tissue of rats and HC11 cell treated with TVA was higher than in the control group. Our results suggest that the identified proteins may be related to CIA biosynthesis in mammary tissue. Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | PROTEIN DISULFIDE-ISOMERASE | - |
dc.subject | TRANS-VACCENIC ACID | - |
dc.subject | SMOOTH-MUSCLE-CELLS | - |
dc.subject | HYDROGEN-PEROXIDE | - |
dc.subject | COA DESATURASE | - |
dc.subject | FATTY-ACIDS | - |
dc.subject | ANTIOXIDANT PROPERTIES | - |
dc.subject | GENE-EXPRESSION | - |
dc.subject | MESSENGER-RNA | - |
dc.subject | DIETARY | - |
dc.title | Proteomic analysis of endogenous conjugated linoleic acid biosynthesis in lactating rats and mouse mammary gland epithelia cells (HC11) | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Young-Jun | - |
dc.identifier.doi | 10.1016/j.bbapap.2009.11.016 | - |
dc.identifier.scopusid | 2-s2.0-76849109300 | - |
dc.identifier.wosid | 000275516500012 | - |
dc.identifier.bibliographicCitation | BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v.1804, no.4, pp.745 - 751 | - |
dc.relation.isPartOf | BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS | - |
dc.citation.title | BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS | - |
dc.citation.volume | 1804 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 745 | - |
dc.citation.endPage | 751 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.subject.keywordPlus | PROTEIN DISULFIDE-ISOMERASE | - |
dc.subject.keywordPlus | TRANS-VACCENIC ACID | - |
dc.subject.keywordPlus | SMOOTH-MUSCLE-CELLS | - |
dc.subject.keywordPlus | HYDROGEN-PEROXIDE | - |
dc.subject.keywordPlus | COA DESATURASE | - |
dc.subject.keywordPlus | FATTY-ACIDS | - |
dc.subject.keywordPlus | ANTIOXIDANT PROPERTIES | - |
dc.subject.keywordPlus | GENE-EXPRESSION | - |
dc.subject.keywordPlus | MESSENGER-RNA | - |
dc.subject.keywordPlus | DIETARY | - |
dc.subject.keywordAuthor | Conjugated linoleic acid | - |
dc.subject.keywordAuthor | Trans vaccenic acid | - |
dc.subject.keywordAuthor | Two-dimensional electrophoresis | - |
dc.subject.keywordAuthor | Real-time PCR | - |
dc.subject.keywordAuthor | Stearoyl-CoA desaturase | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.