Inhibitors of nitric oxide production from Artemisia princeps
- Authors
- Li, D.; Han, X.H.; Hong, S.S.; Lee, C.; Lee, M.S.; Lee, D.; Lee, M.K.; Hwang, B.Y.
- Issue Date
- 2010
- Keywords
- Artemisia princeps; Compositae; Nitric oxide production inhibitor; Sesquiterpene lactone
- Citation
- Natural Product Sciences, v.16, no.3, pp.143 - 147
- Indexed
- SCOPUS
KCI
- Journal Title
- Natural Product Sciences
- Volume
- 16
- Number
- 3
- Start Page
- 143
- End Page
- 147
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/118318
- ISSN
- 1226-3907
- Abstract
- The chromatographic separation of a methanol extract of Artemisia princes led to the isolation of two sesquiterpene lactones, artecanin (1) and canin (2), together with a flavonoid, eupatilin (3). Their structures were determined by 1D, 2D-NMR and MS data analysis. All of the isolates were evaluated for their potential to inhibit the LPS-induced production of nitric oxide in murine macrophage RAW 264.7 cells. Compounds 1-3 inhibited nitric oxide production with IC50 values of 19.5, 20.4 and 25.1 μM, respectively.
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- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Plant Biotechnology > 1. Journal Articles
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