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Inhibition of Pathogen Adhesion to Host Cells by Polysaccharides from Panax ginseng
- Issue Date
- 1월-2009
- Publisher
- TAYLOR & FRANCIS LTD
- Keywords
- polysaccharide; Panax ginseng; anti-adhesion; pathogenic bacteria
- Citation
- BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, v.73, no.1, pp.209 - 212
- Indexed
- SCIE
SCOPUS
- Journal Title
- BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Volume
- 73
- Number
- 1
- Start Page
- 209
- End Page
- 212
- ISSN
- 0916-8451
- Abstract
- PG-F2 and PG-HMW from Panax ginseng are pectintype polysaccharides and PG-HMW might be an arabinogalactan. They demonstrated strong anti-adhesive activities against oral and skin pathogens to host cell lines in a dose-dependent manner from 0.1 to 2.0 mg/ml. While enzymatic hydrolysis caused complete loss of anti-adhesive activities, partial hydrolysis produced oligosaccharides with anti-adhesive properties. PG-F2 and PG-HMW might have a selective anti-adhesive effect against certain pathogenic bacteria without adverse effects on commensal bacteria.
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