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Bioactive constituents of the stem bark of Mitrephora glabra
- Authors
- Li, C.; Lee, D.; Graf, T.N.; Phifer, S.S.; Nakanishi, Y.; Riswan, S.; Setyowati, F.M.; Saribi, A.M.; Soejarto, D.D.; Farnsworth, N.R.; Falkinham, III J.O.; Kroll, D.J.; Kinghorn, A.D.; Wani, M.C.; Oberlies, N.H.
- Issue Date
- 2009
- Citation
- Journal of Natural Products, v.72, no.11, pp.1949 - 1953
- Indexed
- SCOPUS
- Journal Title
- Journal of Natural Products
- Volume
- 72
- Number
- 11
- Start Page
- 1949
- End Page
- 1953
- ISSN
- 0163-3864
- Abstract
- Bioactivity-guided fractionation of the stem bark of Mitrephora glabra yielded nine compounds, comprising three entkaurenoids (1-3), five polyacetylenic acids/esters (4-8), and one aporphine alkaloid, liriodenine (9). The structures of the six new compounds (1-3, 5, 7, and 8) were determined by spectroscopic data interpretation. All compounds were evaluated for their inhibitory activities against a panel of cancer cell lines and a battery of microorganisms. © 2009 American Chemical Society and American Society of Pharmacognosy.
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Collections - Graduate School > Department of Plant Biotechnology > 1. Journal Articles
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Related Researcher
- Lee, Dong ho
- Department of Plant Biotechnology