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Potential probiotic properties of Lactococcus lactis NK34 isolated from jeotgal
- Authors
- Lee, Na-Kyoung; Noh, Ji Eun; Choi, Gui-Hun; Park, Eunju; Chang, Hyo-Ihl; Yun, Cheol-Won; Kim, Seung-Wook; Kang, Chang-Won; Yoon, Yoh-Chang; Paik, Hyun-Dong
- Issue Date
- 10월-2007
- Publisher
- KOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST
- Keywords
- Lactococcus lactis; jeotgal; probiotics; cholesterol-lowering activity; immunolstimulating activity; DNA damage
- Citation
- FOOD SCIENCE AND BIOTECHNOLOGY, v.16, no.5, pp.843 - 847
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- FOOD SCIENCE AND BIOTECHNOLOGY
- Volume
- 16
- Number
- 5
- Start Page
- 843
- End Page
- 847
- ISSN
- 1226-7708
- Abstract
- Strain NK34 was characterized for probiotic use. Strain NK34 was named Lactococcus lactis NK34 based on API 50 CHL kit results and 16S rDNA sequencing. L lactis NK34 was highly resistant to artificial gastric juice (pH 2.5) and artificial bile acid. Based on results from the API ZYM kit, 4 enzymes were produced. L. lactis NK34 was resistant to all antibiotics tested except for 10 mu g/mL roxithromycin and 10 mu g/mL erythromycin. The cholesterol-lowering effect of L lactis NK34 was about 46.9%. Concentrations of interleukin (IL)-1 alpha in the 20x concentrated supernatant of L. lactis NK34 was about 361 pg/mL. L lactis NK34 was also found to inhibit the growth of colon cancer cells due to MNNG-induced DNA damage. These results demonstrate the potential of L lactis NK34 as a health-promoting probiotic.
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