Associations of Serum Vitamin D Level with Sarcopenia, Non-Alcoholic Fatty Liver Disease (NAFLD), and Sarcopenia in NAFLD Among People Aged 50 Years and Older: The Korea National Health and Nutrition Examination Survey IV-V
DC Field | Value | Language |
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dc.contributor.author | Hong, Jihye | - |
dc.contributor.author | Shin, Woo-Kyoung | - |
dc.contributor.author | Lee, Jung Woo | - |
dc.contributor.author | Lee, Seung-Yeon | - |
dc.contributor.author | Kim, Yookyung | - |
dc.date.accessioned | 2022-02-23T13:41:13Z | - |
dc.date.available | 2022-02-23T13:41:13Z | - |
dc.date.created | 2022-02-15 | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 1540-4196 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/136628 | - |
dc.description.abstract | Background: The role of serum 25-hydroxyvitamin D [25(OH)D] levels in the development of sarcopenia in non-alcoholic fatty liver disease (NAFLD) remains controversial. We investigated the association between vitamin D levels, occurrence of sarcopenia, NAFLD, and sarcopenia in NAFLD in adults aged >50 years.Methods: This study used data pertaining to 5396 adults aged >50 years (1870 men and 3526 women) from the 2008-2011 Korea National Health and Nutrition Examination Survey. Appendicular skeletal muscle mass adjusted by weight (ASM/Wt) was used to diagnose sarcopenia, and NAFLD was diagnosed using the NAFLD fat score.Results: The lowest quintile of serum 25(OH)D level (4.85-15.26 ng/mL) was associated with an increased occurrence of sarcopenia [odds ratio (OR) 2.65; 95% confidence interval (CI) 1.64-4.27], NAFLD (OR 1.82; 95% CI 1.19-2.96), and sarcopenia in NAFLD (OR 2.25; 95% CI 1.26-4.03) in men. In women, sarcopenia (OR 1.80; 95% CI 1.29-2.51) was also significantly associated with serum vitamin D levels, whereas high levels of vitamin D were not significantly related to NAFLD.Conclusions: Serum vitamin D levels are associated with sarcopenia, NAFLD, and sarcopenia in NAFLD. Vitamin D level can be a useful marker of sarcopenia and NAFLD, especially in men. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MARY ANN LIEBERT, INC | - |
dc.subject | METABOLIC SYNDROME | - |
dc.subject | INSULIN-RESISTANCE | - |
dc.subject | RISK-FACTORS | - |
dc.subject | OBESITY | - |
dc.subject | STEATOHEPATITIS | - |
dc.subject | METAANALYSIS | - |
dc.subject | PREVALENCE | - |
dc.title | Associations of Serum Vitamin D Level with Sarcopenia, Non-Alcoholic Fatty Liver Disease (NAFLD), and Sarcopenia in NAFLD Among People Aged 50 Years and Older: The Korea National Health and Nutrition Examination Survey IV-V | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Yookyung | - |
dc.identifier.doi | 10.1089/met.2021.0106 | - |
dc.identifier.scopusid | 2-s2.0-85130745632 | - |
dc.identifier.wosid | 000749850100001 | - |
dc.identifier.bibliographicCitation | METABOLIC SYNDROME AND RELATED DISORDERS, v.20, no.4, pp.210 - 218 | - |
dc.relation.isPartOf | METABOLIC SYNDROME AND RELATED DISORDERS | - |
dc.citation.title | METABOLIC SYNDROME AND RELATED DISORDERS | - |
dc.citation.volume | 20 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 210 | - |
dc.citation.endPage | 218 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Early Access | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.subject.keywordPlus | METABOLIC SYNDROME | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordPlus | STEATOHEPATITIS | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordAuthor | skeletal muscle index | - |
dc.subject.keywordAuthor | muscle mass | - |
dc.subject.keywordAuthor | nonalcoholic steatohepatitis | - |
dc.subject.keywordAuthor | serum vitamin D | - |
dc.subject.keywordAuthor | aging | - |
dc.subject.keywordAuthor | KNHANES | - |
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