In Vitro Prebiotic and Anti-Colon Cancer Activities of Agar-Derived Sugars from Red Seaweeds
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yun, Eun Ju | - |
dc.contributor.author | Yu, Sora | - |
dc.contributor.author | Kim, Young-Ah | - |
dc.contributor.author | Liu, Jing-Jing | - |
dc.contributor.author | Kang, Nam | - |
dc.contributor.author | Jin, Yong-Su | - |
dc.contributor.author | Kim, Kyoung | - |
dc.date.accessioned | 2022-03-04T02:41:21Z | - |
dc.date.available | 2022-03-04T02:41:21Z | - |
dc.date.created | 2022-02-09 | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 1660-3397 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/137694 | - |
dc.description.abstract | Numerous health benefits of diets containing red seaweeds or agar-derived sugar mixtures produced by enzymatic or acid hydrolysis of agar have been reported. However, among various agar-derived sugars, the key components that confer health-beneficial effects, such as prebiotic and anti-colon cancer activities, remain unclear. Here, we prepared various agar-derived sugars by multiple enzymatic reactions using an endo-type and an exo-type of beta-agarase and a neoagarobiose hydrolase and tested their in vitro prebiotic and anti-colon cancer activities. Among various agar-derived sugars, agarotriose exhibited prebiotic activity that was verified based on the fermentability of agarotriose by probiotic bifidobacteria. Furthermore, we demonstrated the anti-colon cancer activity of 3,6-anhydro-l-galactose, which significantly inhibited the proliferation of human colon cancer cells and induced their apoptosis. Our results provide crucial information regarding the key compounds derived from red seaweeds that confer beneficial health effects, including prebiotic and anti-colon cancer activities, to the host. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.title | In Vitro Prebiotic and Anti-Colon Cancer Activities of Agar-Derived Sugars from Red Seaweeds | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Kyoung | - |
dc.identifier.doi | 10.3390/md19040213 | - |
dc.identifier.scopusid | 2-s2.0-85105144663 | - |
dc.identifier.wosid | 000643200800001 | - |
dc.identifier.bibliographicCitation | MARINE DRUGS, v.19, no.4 | - |
dc.relation.isPartOf | MARINE DRUGS | - |
dc.citation.title | MARINE DRUGS | - |
dc.citation.volume | 19 | - |
dc.citation.number | 4 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordAuthor | red seaweeds | - |
dc.subject.keywordAuthor | agarose | - |
dc.subject.keywordAuthor | agarotriose | - |
dc.subject.keywordAuthor | 3 | - |
dc.subject.keywordAuthor | 6-anhydro-l-galactose | - |
dc.subject.keywordAuthor | prebiotics | - |
dc.subject.keywordAuthor | anti-colon cancer activity | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.