Detailed Information
Cited 0 time in 
Cited 0 time in 
Cited 0 time in
Metadata Downloads
SIWV tetrapeptide and ROS-responsive prodrug conjugate for advanced glioblastoma therapy
- Authors
- Park, Yoon Kyung; Jangili, Paramesh; Zi, Soyu; Kang, Rae Hyung; Kim, Dokyoung; Kim, Jong Seung
- Issue Date
- 29-9월-2022
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- CHEMICAL COMMUNICATIONS, v.58, no.78, pp.10941 - 10944
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMICAL COMMUNICATIONS
- Volume
- 58
- Number
- 78
- Start Page
- 10941
- End Page
- 10944
- ISSN
- 1359-7345
- Abstract
- A new conjugate formulation, SIWV-PB-SN, based on glioblastoma (GBM)-homing SIWV tetrapeptide and an ROS-responsive prodrug is reported. SIWV-PB-SN selectively penetrates the GBM cells and releases anti-GBM drug (SN-38) via ROS-induced linker cleavage. This study presents a new insight for a more advanced therapeutic approach to overcoming GBM.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Science > Department of Chemistry > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.