Effect of processing method on platycodin D content in Platycodon grandiflorum roots
- Authors
- Kwon, Jaeyoung; Lee, Hyaemin; Kim, Nahyun; Lee, Je-Hyun; Woo, Mi Hee; Kim, Jinwoong; Kim, Yeong Shik; Lee, Dongho
- Issue Date
- Sep-2017
- Publisher
- PHARMACEUTICAL SOC KOREA
- Keywords
- Platycodon grandiflorum; Platycodi Radix; Platycodin D; HPLC-ELSD; Processing method
- Citation
- ARCHIVES OF PHARMACAL RESEARCH, v.40, no.9, pp.1087 - 1093
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- ARCHIVES OF PHARMACAL RESEARCH
- Volume
- 40
- Number
- 9
- Start Page
- 1087
- End Page
- 1093
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/82389
- DOI
- 10.1007/s12272-017-0946-6
- ISSN
- 0253-6269
- Abstract
- Platycodon grandiflorum root is a traditional medicine and food material rich in triterpenoid saponins. Its major constituent, platycodin D (PD), is known to have various pharmacological properties, but processing methods may influence the PD content. In this study, a fully validated HPLC-ELSD method was developed for the quantification of PD in various states of 73 P. grandiflorum root samples from East Asia, and it exhibited a marked variation of the content. Furthermore, the effects of processing procedures such as peeling and drying temperature on the PD content were investigated using UPLC-ELSD analysis, and as a result, a significant influence of processing methods such as peeling and heating of samples on the content was confirmed. Specifically, unpeeled samples that were dried at 40 A degrees C showed the greatest PD content. The obtained results could facilitate the reliable standardization of P. grandiflorum for precise authentication and efficacious applications.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Plant Biotechnology > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholar.korea.ac.kr/handle/2021.sw.korea/82389)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.