Detailed Information
Cited 0 time in 
Cited 0 time in 
Cited 0 time in
Metadata Downloads
Evaluation of the cytotoxicity of gold nanoparticle-quercetin complex and its potential as a drug delivery vesicle
- Issue Date
- 2016
- Publisher
- Korean Society for Applied Biological Chemistry
- Keywords
- Citrate synthesis; Drug delivery system; Gold nanoparticle; Quercetin
- Citation
- Journal of Applied Biological Chemistry, v.59, no.2, pp.145 - 147
- Indexed
- SCOPUS
KCI
- Journal Title
- Journal of Applied Biological Chemistry
- Volume
- 59
- Number
- 2
- Start Page
- 145
- End Page
- 147
- ISSN
- 1976-0442
- Abstract
- Recently, conjugates of medicinal herb-derived bioflavonoids, such as quercetin, and gold nanoparticles (GNPs) have gained attention as targeted drug delivery systems. In the present study, because quercetin is an important flavonoid with anticancer, anti-inflammatory, and anti-oxidant properties, GNP-quercetin complexes (GNPQs) were synthesized to investigate possible adverse effects such as cytotoxicity. We found that while quercetin was cytotoxic, GNPQs were not cytotoxic towards the RAW 264.7 and THP-1 cell lines. Therefore, GNPQs may serve as a potential drug delivery system for cancer treatment. © The Korean Society for Applied Biological Chemistry 2016.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Biosystems and Biotechnology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.