Yeast hydrolysate as a functional anti-obesity ingredient: appetite suppressive effects of yeast hydrolysate in food-deprived mice
- Authors
- Hong, Ki Bae; Jung, Eun Young; Kim, Jae Hwan; Chang, Un Jae; Suh, Hyung Joo
- Issue Date
- Sep-2015
- Publisher
- MATTIOLI 1885
- Keywords
- Yeast hydrolysate; ghrelin; appetite; obesity
- Citation
- PROGRESS IN NUTRITION, v.17, no.3, pp.262 - 264
- Indexed
- SCIE
SCOPUS
- Journal Title
- PROGRESS IN NUTRITION
- Volume
- 17
- Number
- 3
- Start Page
- 262
- End Page
- 264
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/92556
- ISSN
- 1129-8723
- Abstract
- The aim of this study was to investigate the appetite suppression effects of yeast hydrolysate (YH). Male ICR mice (8 weeks old) were randomly divided into three groups (n=6) as follows: Saline group, which was treated with saline (control); YH0.5 group, which was treated with YH 0.5 g/kg BW; and YH1 group, which was treated with YH 1 g/kg BW. At the beginning of the experiment, the mice were intraperitoneally (IP) injected with either saline or YH. The results showed that YH caused a significant attenuation of food intake in fasted mice (p<0.05) and significantly lowered serum ghrelin levels (YH0.5, 2002.22 pg/mL; YH1, 2337.65 pg/mL vs. Saline, 3363.61 pg/mL, p<0.05). This study indicates that the appetite suppression effects of YH is likely explained by the attenuation of ghrelin.
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Collections - College of Health Sciences > School of Biosystems and Biomedical Sciences > 1. Journal Articles
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