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An optimized extraction technique for acetylcholinesterase inhibitors from the Camellia japonica seed cake by using response surface methodology

Authors
Kim, Jae KyeomKim, Cho RongLim, Ho-JeongNam, Sang HaeJoo, Ok SooShin, Dong-HoonShin, Eui-Cheol
Issue Date
7월-2014
Publisher
TAYLOR & FRANCIS LTD
Keywords
Camellia japonica; camellia seed cake; acetylcholinesterase; Alzheimer' s disease; response surface methodology
Citation
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, v.78, no.7, pp.1237 - 1241
Indexed
SCIE
SCOPUS
Journal Title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume
78
Number
7
Start Page
1237
End Page
1241
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/98134
DOI
10.1080/09168451.2014.915723
ISSN
0916-8451
Abstract
The response surface methodology (RSM) was used to optimize the extraction conditions for the acetylcholinesterase (AchE) inhibitory activity and extraction yield from Camellia japonica seed cake. Predicted values for AchE inhibition and extraction yield were 19.41 and 13.35%, respectively, which are in good agreement with the experimental values from validation, suggesting that RSM may provide a useful tool to optimization processes.
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