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Dietary Conjugated Linoleic Acid Increases Endurance Capacity of Mice During Treadmill Exercise

Authors
Kim, Jun HoPark, Hui GyuPan, Jung HoonKim, Sang HoYoon, Ho GeunBae, Gui SeckLee, HyungjaeEom, Seok-HyunKim, Young Jun
Issue Date
10월-2010
Publisher
MARY ANN LIEBERT, INC
Keywords
conjugated linoleic acid; endurance; exercise; glycogen; treadmill
Citation
JOURNAL OF MEDICINAL FOOD, v.13, no.5, pp.1057 - 1060
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF MEDICINAL FOOD
Volume
13
Number
5
Start Page
1057
End Page
1060
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/115606
DOI
10.1089/jmf.2009.1358
ISSN
1096-620X
Abstract
This study was designed to evaluate the effect of dietary conjugated linoleic acid (CLA) on endurance exercise and availability of metabolic substrates in mice. Four-week-old male BALB/c mice were randomized to a control group (normal diet) and a CLA group (normal diet vertical bar 1% CLA). Each animal group received its respective diet for 10 weeks and was subjected to forced running on a treadmill system to estimate their maximum endurance capacity at the end of the experiment. All mice were immediately sacrificed after prolonged exercise, and the major metabolic substrates were measured in serum and liver. The body weights of mice in the CLA group were lower than those of the control group after the 10 weeks. The maximum running time in CLA-fed mice was significantly longer, by 26%, compared to that of the control mice. Dietary CLA decreased the serum concentrations of triglycerides, nonesterified fatty acids, and urea nitrogen and significantly reduced the consumption of liver glycogen. The present study demonstrated that dietary CLA enhances the endurance capacity of mice by increasing fat utilization and reducing the consumption of stored liver glycogen as substrates for energy metabolism.
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Kim, Sang ho
문화스포츠대학 (국제스포츠학부 스포츠과학전공)
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