Acetic acid enhances endurance capacity of exercise-trained mice by increasing skeletal muscle oxidative properties
- Authors
- Pan, Jeong Hoon; Kim, Jun Ho; Kim, Hyung Min; Lee, Eui Seop; Shin, Dong-Hoon; Kim, Seongpil; Shin, Minkyeong; Kim, Sang Ho; Lee, Jin Hyup; Kim, Young Jun
- Issue Date
- 2-9월-2015
- Publisher
- TAYLOR & FRANCIS LTD
- Keywords
- mouse; exercise training; muscle protein expression; oxidative properties; acetic acid
- Citation
- BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, v.79, no.9, pp.1535 - 1541
- Indexed
- SCIE
SCOPUS
- Journal Title
- BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Volume
- 79
- Number
- 9
- Start Page
- 1535
- End Page
- 1541
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/92507
- DOI
- 10.1080/09168451.2015.1034652
- ISSN
- 0916-8451
- Abstract
- Acetic acid has been shown to promote glycogen replenishment in skeletal muscle during exercise training. In this study, we investigated the effects of acetic acid on endurance capacity and muscle oxidative metabolism in the exercise training using in vivo mice model. In exercised mice, acetic acid induced a significant increase in endurance capacity accompanying a reduction in visceral adipose depots. Serum levels of non-esterified fatty acid and urea nitrogen were significantly lower in acetic acid-fed mice in the exercised mice. Importantly, in the mice, acetic acid significantly increased the muscle expression of key enzymes involved in fatty acid oxidation and glycolytic-to-oxidative fiber-type transformation. Taken together, these findings suggest that acetic acid improves endurance exercise capacity by promoting muscle oxidative properties, in part through the AMPK-mediated fatty acid oxidation and provide an important basis for the application of acetic acid as a major component of novel ergogenic aids.
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- Appears in
Collections - College of Science and Technology > Department of Food and Biotechnology > 1. Journal Articles
- College of Culture and Sports > Sport Science in Division of Global Sport Studies > 1. Journal Articles
- Graduate School > Department of Food and Biotechnology > 1. Journal Articles
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