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European Journal of Medicinal Chemistry

Journal Title

  • European Journal of Medicinal Chemistry

ISSN

  • E 1768-3254 | P 0223-5234 | 0223-5234 | 1768-3254

Publisher

  • Elsevier BV
  • Elsevier

Listed on(Coverage)

JCR1997-2019
SJR1999-2019
CiteScore2011-2019
SCI2010-2019
SCIE2010-2021
CC2016-2021
SCOPUS2017-2020
MEDLINE2016-2021
EMBASE2016-2020

Active

  • Active

    based on the information

    • SCOPUS:2020-10

Country

  • FRANCE

Aime & Scopes

  • The European Journal of Medicinal Chemistry is a global journal that publishes studies on all aspects of medicinal chemistry. It provides a medium for publication of original papers and also welcomes critical review papers. A typical paper would report on the organic synthesis, characterization and pharmacological evaluation of compounds. Other topics of interest are drug design, QSAR, molecular modeling, drug-receptor interactions, molecular aspects of drug metabolism, prodrug synthesis and drug targeting. The journal expects manuscripts to present the rational for a study, provide insight into the design of compounds or understanding of mechanism, or clarify the targets.

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Article List

1 - 20 out of 20 results.

SCIESCOPUS
Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson?s disease via the activation of Nrf2/ HO-1 signaling

Lu, Qili; Gouda, Noha A.; Quan, Guofeng; Nada, Hossam; Elkamhawy, Ahmed; Lee, Dongho; Lee, Chang Hoon; Cho, Jungsook; Lee, Kyeong

ArticleIssue Date2022CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.242PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Discovery of novel potent migrastatic Thiazolo[5,4-b]pyridines targeting Lysyl-tRNA synthetase (KRS) for treatment of Cancer metastasis

Lee, Seungbeom; Kwon, Nam Hoon; Seo, Bokyung; Lee, Jin Young; Cho, Hye Young; Kim, Kyeojin; Kim, Hyun Su; Jung, Kiwon; Jeon, Young Ho; Kim, Sunghoon, et al.

ArticleIssue Date2021CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.218PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Discovery and optimization of novel 3-benzyl-N-phenyl-1H-pyrazole-5-carboxamides as bifunctional antidiabetic agents stimulating both insulin secretion and glucose uptake

Jo, Jeyun; Lee, Dahae; Park, Yeong Hye; Choi, Hyeonjin; Han, Jinhee; Park, Do Hwi; Choi, You-Kyung; Kwak, Jinsook; Yang, Min-Kyu; Yoo, Jin-Wook, et al.

ArticleIssue Date2021CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.217PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl)pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors

Ali, E.M.H.; El-Telbany, R.F.A.; Abdel-Maksoud, M.S.; Ammar, U.M.; Mersal, K.I.; Zaraei, S.-O.; El-Gamal, M.I.; Choi, S.-I.; Lee, K.-T.; Kim, H.-K., et al.

ArticleIssue Date2021CitationEuropean Journal of Medicinal Chemistry, v.215PublisherElsevier Masson s.r.l.
SCIESCOPUS
Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers

Choi, Seung-Hye; Ryu, SeongShick; Sim, Kyoungmi; Song, Chiman; Shin, Injae; Kim, Seong-Seop; Lee, Young-Sun; Park, Jae-Yong; Sim, Taebo

ArticleIssue Date2020CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.208PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
2-Anilinoquinoline based arylamides as broad spectrum anticancer agents with B-RAFV600E/C-RAF kinase inhibitory effects: Design, synthesis, in vitro cell-based and oncogenic kinase assessments

El-Damasy, A.K.; Haque, M.M.; Park, J.W.; Shin, S.C.; Lee, J.-S.; EunKyeong, Kim E.; Keum, G.

ArticleIssue Date2020CitationEuropean Journal of Medicinal Chemistry, v.208PublisherElsevier Masson s.r.l.
SCIESCOPUS
Pyrazole derived ultra-short antimicrobial peptidomimetics with potent anti-biofilm activity

Ahn, Mija; Gunasekaran, Pethaiah; Rajasekaran, Ganesan; Kim, Eun Young; Lee, Soo-Jae; Bang, Geul; Cho, Kun; Hyun, Jae-Kyung; Lee, Hyun-Ju; Jeon, Young Ho, et al.

ArticleIssue Date2017CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.125, pp.551 - 564PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor

Yoon, Hojong; Shin, Injae; Nam, Yunju; Kim, Nam Doo; Lee, Kyung-Bok; Sim, Taebo

ArticleIssue Date2017CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.125, pp.1145 - 1155PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity

Kim, Youngjae; Park, Hyeri; Lee, Jeongeun; Tae, Jinsung; Kim, Hak Joong; Min, Sun-Joon; Rhim, Hyewhon; Choo, Hyunah

ArticleIssue Date2016CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.123, pp.180 - 190PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Design, synthesis and biological evaluation of PSMA/hepsin-targeted heterobivalent ligands

Subedi, Milan; Minn, Ii; Chen, Jianbo; Kim, YunHye; Ok, Kiwon; Jung, Yong Woo; Pomper, Martin G.; Byun, Youngjoo

ArticleIssue Date2016CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.118, pp.208 - 218PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer

Agarwal, Hitesh K.; Khalil, Ahmed; Ishita, Keisuke; Yang, Weilian; Nakkula, Robin J.; Wu, Lai-Chu; Ali, Tehane; Tiwari, Rohit; Byun, Youngjoo; Barth, Rolf F., et al.

ArticleIssue Date2015CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.100, pp.197 - 209PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Synthesis and biological evaluation of new pyrazol-4-ylpyrimidine derivatives as potential ROS1 kinase inhibitors

Abdelazem, A.Z.; Al-Sanea, M.M.; Park, B.S.; Park, H.M.; Yoo, K.H.; Sim, T.; Park, J.B.; Lee, S.-H.; Lee, S.H.

ArticleIssue Date2015CitationEuropean Journal of Medicinal Chemistry, v.90, pp.195 - 208PublisherElsevier Masson SAS
SCIESCOPUS
Synthesis and biological evaluation of 1-(isoxazol-5-ylmethylaminoethyl)-4-phenyl tetrahydropyridine and piperidine derivatives as potent T-type calcium channel blockers with antinociceptive effect in a neuropathic pain model

Lee, Ju-Hyeon; Seo, Seon Hee; Lim, Eun Jeong; Cho, Nam-Chul; Nam, Ghilsoo; Kang, Soon Bang; Pae, Ae Nim; Jeong, Nakcheol; Keum, Gyochang

ArticleIssue Date2014CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.74, pp.246 - 257PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Novel pyrimidoazepine analogs as serotonin 5-HT2A and 5-HT2C receptor ligands for the treatment of obesity

Yang, Ha Yun; Tae, Jinsung; Seo, Yong Wan; Kim, Yoon Jung; Im, Hye Yeon; Choi, Gil Don; Cho, Heeyeong; Park, Woo-Kyu; Kwon, Oh Seung; Cho, Yong Seo, et al.

ArticleIssue Date2013CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.63, pp.558 - 569PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Synthesis and biological evaluation of novel aliphatic amido-quaternary ammonium salts for anticancer chemotherapy: Part II

Yang, Jee Sun; Song, Doona; Ko, Won Jin; Kim, Bunyea; Kim, Bo-Kyung; Park, Song-Kyu; Won, Misun; Lee, Kiho; Lee, Kyeong; Kim, Hwan Mook, et al.

ArticleIssue Date2013CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.63, pp.621 - 628PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Synthesis and evaluation of oxime derivatives as modulators for amyloid beta-induced mitochondrial dysfunction

Kim, Young Seub; Jung, Sun Hwa; Park, Beoung-Geon; Ko, Min Kyung; Jang, Hyun-Seo; Choi, Kihang; Baik, Ja-Hyun; Lee, Jiyoun; Lee, Jae Kyun; Pae, Ae Nim, et al.

ArticleIssue Date2013CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.62, pp.71 - 83PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Synthesis of a novel series of 2-alkylthio substituted naphthoquinones as potent acyl-CoA: Cholesterol acyltransferase (ACAT) inhibitors

Lee, Kyeong; Cho, Soo Hyun; Lee, Jee Hyun; Goo, Jail; Lee, Sung Yoon; Boovanahalli, Shanthaveerappa K.; Yeo, Siok Koon; Lee, Sung-Joon; Kim, Young Kook; Kim, Dong Hee, et al.

ArticleIssue Date2013CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.62, pp.515 - 525PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Synthesis and biological evaluation of novel aliphatic amido-quaternary ammonium salts for anticancer chemotherapy: Part I

Yang, Jee Sun; Song, Doona; Lee, Boah; Ko, Won Jin; Park, Song-Kyu; Won, Misun; Lee, Kiho; Kim, Hwan Mook; Han, Gyoonhee

ArticleIssue Date2011CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.46, no.7, pp.2861 - 2866PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
HIF-1 alpha inhibitors: Synthesis and biological evaluation of novel moracin O and P analogues

Xia, Yan; Jin, Yinglan; Kaur, Navneet; Choi, Yongseok; Lee, Kyeong

ArticleIssue Date2011CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.46, no.6, pp.2386 - 2396PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCIESCOPUS
Synthesis of (S)-(+)-decursin and its analogues as potent inhibitors of melanin formation in B16 murine melanoma cells

Lee, Kyeong; Lee, Jee-Hyun; Boovanahalli, Shanthaveerappa K.; Choi, Yongseok; Choo, Soo-Jin; Yoo, Ick-dong; Kim, Dong Hee; Yun, Mi Young; Lee, Gye Won; Song, Gyu-Yong

ArticleIssue Date2010CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.45, no.12, pp.5567 - 5575PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
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