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Ameliorating Effects of a Nopal (Opuntia ficus-indica) Complex on Blood Glucose in db/db Mice
- Issue Date
- Feb-2011
- Publisher
- KOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST
- Keywords
- Opuntia ficus-indica; hypoglycemic; insulin; pancreatic islet; db/db mice
- Citation
- FOOD SCIENCE AND BIOTECHNOLOGY, v.20, no.1, pp.255 - 259
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- FOOD SCIENCE AND BIOTECHNOLOGY
- Volume
- 20
- Number
- 1
- Start Page
- 255
- End Page
- 259
- ISSN
- 1226-7708
- Abstract
- This study investigated the effects of a nopal (Opuntia ficus-indica) complex (OF) on blood glucose metabolism in db/db mice for 4 weeks. Food and water intake significantly decreased in OF-treated mice compared to controls (p < 0.05). In addition, blood glucose and plasma insulin levels were significantly reduced in the OF-treated group compared to the controls (p < 0.05). Histopathological analysis showed that the morphology of pancreatic islets was improved in the OF-treated db/db mice. Immunohistochemistry of the pancreatic islets showed that insulin production and the number of beta-cells apparently increased.
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Related Researcher
- Lee, Sung Joon
- College of Life Sciences and Biotechnology (Division of Food Bioscience and Technology)